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Viagra (Sildenafil citrate), which millions of men take for erectile dysfunction (ED), reduces the effects of hormonal stress on the heart by half, according to a study published online in the journal Circulation. Viagra causes genital blood vessels to expand, which helps in maintaining an erection. Recent research also has pointed to its potential usefulness in treating pulmonary hypertension. Prior to the latest findings by a team of Johns Hopkins researchers, it was thought to have little effect on the heart. Viagra, or sildenafil, blunts the strengthened heart beat caused by chemically induced stress, according to study senior author and cardiologist David Kass, MD, a professor at the Johns Hopkins University School of Medicine and its Heart Institute. It thereby lessens both the excess amount of blood and the force used to pump it to the body. "Sildenafil effectively puts a 'brake' on chemical stimulation of the heart," says Kass. Prevents and Reverses Effects of High BP These findings are believed to be the first confirmation in humans that Viagra has a direct effect on the heart. In earlier research, Kass and his team observed a similar effect in mice; Sildenafil blocked the short-term effects of hormonal stress in the heart. Related studies by the group show that sildenafil also prevents and reverses the long-term effects of chronic high blood pressure on the heart. Sildenafil reversed the negative effects on heart muscle weakened by heart failure and enlargement -- a condition called hypertrophy -- in mouse experiments Kass and his team carried out earlier this year. They reported their results in the journal Nature Medicine. "But we had no firm evidence as to whether or how this therapy might work in the human heart," says Kass. "Our latest research provides firm evidence this drug does indeed have an important impact on the heart." Increased Heartbeat Was Slowed Thirty-five healthy men and women, with an average age of 30 and no previous signs of coronary artery disease, participated in the six-month Johns Hopkins study. Within a three-hour timeframe, each participant received two separate injections of dobutamine (5 micrograms per kilogram for five minutes), a synthetic, adrenaline-like chemical that increases heart rate and pumping strength. Between injections, study participants were assigned randomly to a group that was treated with sildenafil (100 milligrams taken orally) or to a group given a sugar pill placebo. All participants then were given the second dobutamine injection to see what effects sildenafil or placebo had on the heart. Measurements of heart function were made before and after each injection. These included blood pressure readings, electrocardiograms and echocardiograms. Blood samples confirmed relatively equal levels of sildenafil and other enzymes. Each dobutamine injection stimulated heart function, increasing heart rate and the force of each heartbeat used to pump blood throughout the body, results showed. "This stimulation is similar to the way the nervous system normally increases heart function when triggered by emotional or exercise stress, or in diseases such as heart failure," notes Kass. After the first injection of dobutamine, the force of heart contraction increased by 150 percent in both groups. In the placebo group, this increase repeated itself after the second injection. However, in the group treated with sildenafil, the increased heartbeat was slowed by 50 percent, resulting in a smaller increase in blood flow and blood pressure generated by the heart in response to chemical stimulation. Between injections, heart function was not altered in the sildenafil group, demonstrating the absence of adverse side effects on the resting human heart. Stops PDE5A Action "Knowing more about the effects of sildenafil on heart function will allow for safer evaluation of its use as a treatment for heart problems," says Kass. "Our results set the stage for further studies of sildenafil's immediate and long-term effects on the heart and its ability to modify other neurohormonal and stress stimuli, including adrenaline and hypertension," he adds. While the precise biological actions of sildenafil in the heart are not fully understood, the drug is known to work by stopping the action of an enzyme, called phosphodiesterase 5 (PDE5A), Kass explains. This enzyme is involved in the breakdown of a key molecule, cyclic GMP, which helps control stresses and limit overgrowth in the heart. PDE5A is also the biological pathway that sildenafil blocks in the penis to prevent the relaxation of blood vessels and thus maintain erections. Copyright 2005 Daily News Central manual penis elargement penis enlargment tool pennis enlargement before and after do penile enlargement pills really work free exercise tip for penis enlagement penis enlarement herb vigrx penis enlagement pill penis enlargement testimonials

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Ever been confused by all the overwhelming information and different strategies to cure premature ejaculation? Let me show you the top 5 misleading suggestions I've uncovered on the web. Many common 'solutions' to prevent premature ejaculation are completely counterproductive. Anyone who is familiar with my writing or my work as a sexual healer will understand what I mean. To successfully treat premature ejaculation or increase sexual stamina it is important to experience a sexual moment deeply and completely. Many of the premature ejaculation remedies available today come from the opposite perspective. Let's run through a few of these techniques that take you further away from sexual fulfillment and satisfaction. 1. Numbing Creams / Sprays / Extra condoms Numb says it all. What's the point of sex if you're not really feeling it. Your partner doesn't want a human vibrator. Trust me, there's a time for toys and there's a time for a real live man. I don't want mine with extra layers of latex and dead nerve endings thankyou very much. When I have a man inside me I want to know he is feeling it! Plus, I've heard that that those numbing potions can affect the woman during sex. Imagine that, two people going through the motions without feeling it! 2. Distracting Yourself A lot of folklore about male sexual performance revolves around the idea of delaying orgasm by distracting yourself. Thinking about your mother-in-law or sports, biting your cheek etc are all methods I have heard of or read about at some time or another. Turning off your arousal temporarily is not the same as mastering it. And again, if you only able to have sex by thinking about boring or distasteful things, how much fun is it going to be? This is a bad habit to get into. You don't want to train yourself to get bored and distracted when you are in the middle of hot lovin'. No woman is ever going to be interested in a man who can't focus on the matter at hand. Especially if she figures out you are thinking about your mother-in-law!! 3. Masturbation This is an interesting one. Remember that scene in 'Something About Mary' where he 'clears the pipes' before his big date to avoid seeming desperate. I have read that it is a good thing before sex to have a pre-emptive orgasm in order to delay the main event. I'd like to examine this a bit closer to see where this isn't helpful and maybe highlight when it is. Anxiety and stress about the impending sexual experience, thinking about the possibility of embarrassing yourself by coming too soon and focusing on the negatives of your sexual performance WHILE you masturbate is extremely unhelpful. Building a regime of this can be very damaging. It will have the effect of eroticising and reinforcing these aspects. You will associate orgasm even more with the stress and performance anxiety that is already a problem. However masturbating as part of a relaxed regime of self-pleasure and self-love can be very helpful. As long as your masturbation is not tied to your sexual performance it can be an enriching part of your sex life. In particular using self-pleasure to more fully explore your sexual arousal levels, orgasms, and control is the first step to deepening your awareness of sex. 4. Muscle Control Some techniques are like shaolin kung-fu disciplines that prescribe pelvic floor exercises. The theory is that with enough muscle strength and control you can prevent ejaculation escaping. By catching it with intense muscle contractions! Pretty spectacular stuff hey? In reality it's a bit like shutting the gate after the horse has bolted. Wouldn't you rather devote your time to exercises that help you understand your arousal levels so you can control the orgasm beforehand, and not just the fluid after the fact. And by the way, from what I gather it's extremely difficult to achieve anyway. 5. Alcohol / Drugs Relying on alcohol or drugs before you initiate a sexual encounter is a definite no no. Alcohol ultimately depresses your nervous system. And so depresses your ability to feel and maintain an erection. It is certainly the last thing you want to rely on for great sex. It may seem that you might loosen up your inhibitions temporarily. From the point of view of sexual stamina, forget it! And drugs - recreational or therapeutic. Some may give the illusion of increased sexual performance. But ultimately it is your level of awareness, your level of consciousness, your level of presence as a man that makes all the difference. I don't want you to think I'm a complete prude. This stuff isn't terrible in and of itself. I like the odd glass of champagne as much as the next girl. But my point is this. Using any or all of these techniques as the basis of your premature ejaculation cure will fail. It could actually make the situation worse. Relying on these things will lead you further from your true goal of sexual mastery and control of your orgasms. The only way to become a master of your sexuality is to go deeper into your sexual experiences, not further away. Learn about your body and orgasmic arousal by focusing on them. Don't shut your sexuality down in the quest for the 'appearance' of sexual mastery. A man with a numb penis, thinking about sports, thrusting for an hour, is about as far from a master as you can get. Love, Mukee Okan Copyright 2005 Mukee Okan cheap penis enhancement penis enlargment procedure enlargement penis pill vimax free penis enlagement video free penile enlargment technique best pennis enlargement penis enargement stretcher male pennis enlargement penis enhancement pills review

Ever heard of arousal step-down techniques? How about the PC muscle and Kegels? If you're like most guys, you probably haven't. And as such, most men - unaware of the numerous ways they can boost their sexual skill and 'lasting' power - regularly produce mediocre performances in bed, leaving themselves disappointed and the women they're with disillusioned and usually orgasmless. It's a real shame. In a poll, 93% of men asked, said they'd like to last longer in bed before ejaculating - but 100% of those men were unaware of how they could achieve such a seemingly impossible feat. The truth is, it's not impossible (or even difficult) to maximise your sexual performance and attain complete control over how long you boogie for and generally get on down with the ladies. So, let's take a look at one sexual method that'll allow you massive control over your arousal levels and always give you the choice of when to cum or when to continue. During sex, most men begin to lose control of themselves (in terms of ejaculation!) at around the 2 or 3 minute mark - which is usually midway through the first sexual position. And what a letdown ejaculating at this point would be! So, that's usually the first point at which you'll use this technique. It involves two steps. The first takes place in your mind - which is the root of many a male's sexual performance troubles. 1. When you first feel those telltale sensations in your penis (the heightened sensitivity and energy that let you know that if you carry on doing what you're doing you'll soon explode) don't panic! Too many men are pushed over the edge, right to ejaculation, because they mentally begin to panic when they feel they're close to orgasm. Panic phrases rush through their heads, like: "Uh oh, I'm gonna blow!" and "Not again, this is going to be embarrassing." Instead of letting these counter-productive thoughts fill your mind and quicken the onset of orgasm, instead calmly say in your head: "Okay, I'm close to ejaculating. Time to use an arousal step-down technique." Then move onto step number two. 2. The most sensitive part of your penis is the top of the shaft and especially the head. To decrease its stimulation (without stopping the 'action') slowly and deeply thrust into your partner, as far as you can go and she can pleasurably take. Then, gently grind your hips, wiggling your pubic bone (the hard area above your penis, about 8 inches down from your belly button) on her vagina. To her, this seems and feels like a wonderful stroke variation, which gives her external clitoral stimulation (the number one way to make any woman orgasm). However, behind the scenes, it's momentarily decreasing your stimulation, enabling you to last longer. This happens because when you plunge deep into her, your penis enters a wider area of her vagina, which lessens its contact and stimulation. Then, to cap it off, you grind and wiggle, instead of thrusting in and out, which further decreases the intense sensations of sex. After 30 seconds or so, your arousal levels will have dropped enough for you to restart your thrusting. By using this technique, you're able to control your urge to pop without stopping sex and while giving your partner extra sexual stimulation. Now how much better a technique is that for tackling premature ejaculation when compared to what most people consider to be effective techniques? Things like: "Count backward from 100" and "Think of dead puppies!" Sex, as you well know, is all about fun. Using the 2-step technique above, you can fully enjoy the experience - without the worry of it all being over too soon! penis enlagement pill pro solution top rated penis enlarement pills penis enhancement program vimax manual penis enlargement exercise penis enlagement technique penis enlagement result pennis enlargement tool manual pennis enlargement penis enhancement pills review

KNOWING ROSACEA Rosacea is a disorder of the blood vessels. It is a common skin disorder. Approximately 48 percent of the world population suffers from Rosacea. However, Rosacea is one of the most misunderstood states of the skin. FAMOUS PERSONS SUFFERING FROM ROSACEA If you are having Rosacea, you are then in the august company of eminent persons. A few of the noted personalities suffering from Rosacea are JP Morgan, WC Fields, Cameron Diaz, Bill Clinton, Prince Harry of England, besides the late princess of Wales and mother of Prince Harry – Diana. ROSACEA SYMPTOMS The common symptom of rosacea is transformation of the skin color into red. The body portions most affected by rosacea are the cheeks, nose and forehead. At times, such redness and flushing of skin can also spread to the ears, scalp, chest or the neck. As Rosacea progresses, the reddish tinge can turn into a permanent condition. There can also be a marked visibility of the small blood vessels particularly at the skin surface, stinging or burning skin sensation, eyes turning gritty and reddish, and pus-filled or simple bumps that appear red. Among these severe symptoms are bulbous noses. The maiden rosacea symptoms are nagging redness which is often wrongly attributed to cleansing, exercising or temperature changes. SIMILAR SKIN DISORDERS Many confuse rosacea with seborrheic dermatitis or/and acne vulgaris. Mentionably, rosacea can co-exist with acne vulgaris and seborrheic dermatitis. THE ROSACEA VULNERABLE SECTION It has been generally noticed that the people with fair skin are the most vulnerable section with reference to rosacea. Therefore, rosacea does have a hereditary strain. Those having a descent from the Celtic or the fair-skinned European stocks are genetically inclined to suffer from rosacea. Notably, both the sexes can fall prey to rosacea. People of all ages can be affected by rosacea. It has also been noticed that people in the age group of 30-50 are easily affected by rosacea. Nonetheless, women in their middle ages are the most vulnerable section of the populace. The reason is, of course, menopause-abetted hot flushes. However, rosacea symptoms are more severe with reference to men. CAUSES OF ROSACEA There is no unanimity among the medical researchers as to the exact rosacea pathogenesis. Nonetheless, there is a concurrence in views insofar as to the cause of rosacea. Rosacea occurs when stimuli repeatedly dilate the blood vessels, and as a result of which the blood vessels get damaged. The damaged blood vessels dilate rather easily. Besides they either remain permanently dilated or stay dilated for a considerably long time. The consequence is redness of the affected portion and its flushing. ROSACEA PAPULES OR INFLAMMATORY PUSTULES The papule or inflammatory pustule can be I the form of a boil, or a pimple, or an eruption for that matter. In rosacea (papulopustular), the mediators (inflammatory ones) as well as immune cells ooze out from the skin bed that is basically micro-vascular by nature. This, in turn, leads to the inflammatory pustule or papule. OTHER CAUSES OF ROSACEA Various conditions can also lead to rosacea. One thing is for sure: strenuous movements cause blushing and flushing. A few of the situations where such flushing or blushing can be formed are as follows: Stress, cold weather, acute sunburn, and extreme heat exposure especially from the sun. Rosacea can also be caused by sudden changes in temperatures while traveling, or in heated rooms especially in winter. FOODS CAN ALSO CAUSE ROSACEA Certain food items that contain very high quantity of histamine have been identified as responsible for the eruption of rosacea symptoms in many people. Similarly, spicy food besides alcoholic substances can definitely trigger off rosacea. MEDICATIONS TOO CAN LEAD TO ROSACEA Several topical irritants and medications may at times cause rosacea. Take for example several drugs people take to hide wrinkles or to deal with acnes. Among these chemicals those particularly responsible for causing rosacea are tretinoin, benzoyl peroxide, isotretinoin, microdermabrasion, and certain chemical peels. Obviously, one should immediately stop the use of any such irritants the moment any rosacea symptoms appear. INDUCED (STEROID) ROSACEA The term ‘steroid induced rosacea’ points to such rosacea symptoms that are caused by steroids, particularly nasal and topical. Notably, these types of steroids are generally prescribed for patients suffering from seborrheic dermatitis. First aid: In such circumstances, immediately consult the physician. Moreover, one should begin the medication discontinuing process over a period of time. Decrease the dosages slowly. Else there may be a flare up of the rosacea symptoms. MITES & BACTERIA CAN CAUSE ROSACEA AS WELL A considerable number of rosacea people have been found to possess the species of mites known as demodex. This is more so the case with those people who have rosacea from steroids. Mentionably, the presence of a large number of these demodex mites can only cause rosacea. But, they cannot by themselves cause the rosacea condition. The demodex mites will have tom act in conjunction with other factors to be able to trigger off the rosacea states. Bacteria, especially the intestinal bacteria, can cause rosacea. These intestinal bacteria reside in our digestive highways. This is a neurological dysfunction. Such rosacea conditions can erupt after the intestinal bacteria activate the plasma kakllikrein-kinin system. THE KAKLLIKREIN-KININ SYSTEM The kakllikrein-kinin system or the kinin-kallikrein system or just the kinin system is a not well delineated structure of blood proteins. The blood proteins have a major role to play in causing pain, coagulation, control of blood pressure and inflammation. Mentionably, the major mediators of the kinin system are bradykinin and kallidin. Both of them act on different cell types. Both are vasodilators DIFFERENT FORMS OF ROSACEA Researchers have identified four forms of rosacea. Each of these subtypes can have its typical symptoms. More importantly, one person can have more then one of the subtypes at the same time. THE ROSACEA SUBTYPES The four rosacea subtypes are Ocular rosacea, Phymatous rosacea, Papulopustular rosacea and Erythematotelangiectatic rosacea. OCULAR ROSACEA Ocular rosacea mainly affects the eyes. The Ocular rosacea symptoms are burning and itching besides sensations as if there are foreign bodies within the eyes. When anyone is affected by ocular rosacea, the eyes and the eyelids turn dry and red. Irritation of the eyes and the eyelids is also very common. PHYMATOUS ROSACEA Phymatous rosacea affects the nose, ears, cheeks, forehead, chin and the eyes. Phymatous rosacea is also linked with the nose enlargement dysfunction called rhinophyma. Another disorder closely connected with phymatous rosacea is the visibility of small blood vessels near the skin surface. Other symptoms of phymatous rosacea are appearance of irregular surfaces on the skin and which may be also accompanied by nodularities. The skin can get thick as well. PAPULOPUSTULAR ROSACEA Many confuse Papulopustular rosacea with acne. However, Papulopustular rosacea remain reddish while acne do not. The common Papulopustular rosacea symptoms are papules (red bumps) filled with pus. Such bumps are called pustules. Papulopustular rosacea papules with or without pustules generally dissolve within five days. People having Papulopustular rosacea usually have permanent redness of their skin. This state is described medically as erythema. Another symptom of Papulopustular rosacea is they tend to flush or blush quite easily. Moreover, the patient can also have burning or itching sensations. ERYTHEMATOTELANGIECTATIC ROSACEA Erythematotelangiectatic rosacea causes the small blood vessels to appear rather prominently near the surface of the skin. This typical state is known as telangiectasias. TREATING ROASAEA There are various treatments for rosacea people. The strategies vary depending on the acuteness and the rosacea subtype that a particular person may be suffering from. Hence, there can be different treatments for different persons suffering from the rosacea symptoms. Hence, the dermatologists opt for the sub-type-directed method to diagnose, analyze and treat rosacea. LASER TREATMENT Laser treatment in dermatology is variously known as Broad spectrum (Intense Pulsed Light), or Single wavelength (Vascular laser). Laser treatment is one of the most popular treatment methods of rosacea. In laser treatment, light is made to infiltrate the epidermis. The light hits the skin’s dermis layer. It targets the dermis capillaries. The oxy-haemoglobin gets heated up after it absorbs the light. The process heats up the capillary walls till 70 degree centigrade. This heat destroys the capillary walls. The damaged walls are then absorbed by the body via its defence mechanism. CO2 LASER TREATMENT Focused thin beams of CO2 laser are manipulated to defocus or cut (as scalpels) the tissues. Then these tissues are vaporized. CO2 lasers are used to get rid of the excessive tissues formed by phymatous rosacea. In this method, our skin directly absorbs the CO2 lasers wavelength. SIMPLE STEPS TO TACKLE ROSACEA (i) Gentle skin cleansing regime Always deal with the skin gently and lovingly. Go for only those cleansers that are non-irritating. (ii) Shielding skin from sun Never venture out in the sun-bated beach sans protection shields. Regularly use sunscreens. Choose such a sunscreen that consists of a physical blocker agent. Such active blockers are titanium dioxide or zinc oxide. (iii) Trigger avoidance It is important to maintain a diary of the foods and the climatic or other factors that generally lead to rosacea. In fact, The National Rosacea Society promotes this habit. This approach also goes a long way in identification and reduction of the triggers. Moreover, trigger avoidance is ideal to control the onset frequency of rosacea. But, all alone it cannot check rosacea. Nonetheless, the mild rosacea attacks can be effectively checked if a patient avoids the factors that triggered off the rosacea symptoms. One can get flushing after consuming red wine or food items having high quantities of histamine. Then, go for antihistamines. Some common antihistamines are loratadine or cetirizine. (iv) Eyelid hygiene Eyelid hygiene is especially recommended for persons complaining of eyelid infections. Practice eyelid hygiene frequently. Here are some easy eyelid hygiene steps. Gently scrub the eyelids daily; You can use baby shampoo in a diluted form; Or, you can also opt for any across-the-counter eyelid cleaner. Apply the cleaner in warm compresses. But, mind you, never should it be hot. Carry on the practice several times in a day. MEDICATIONS (ii) Topical & Oral Antibiotics To get instant relief from the rash, redness, inflammation, pustules and papules, you can go for topical and oral antibiotics. An effective topical antibiotic is metronidazole. Similarly, ideal oral antibiotics are the tetracycline antibiotics. Some examples of tetracycline antibiotics are minocycline, doxycycline, and tetracycline. The oral antibiotics are rather effective in treating ocular rosacea symptoms. Isotretinoin is generally given to patients who complain of persistent pustules or papules. However, there are several side effects of isotretinoin. Therefore, isotretinoin is prescribed only in acute situations. It is also given to treat acute acne. Nevertheless, for patients suffering from phymatous and papulopustular rosacea, low dosages of isotretinoin have been delivering the goods. BETA BLOCKERS OR α-2 AGONIST The commonly used α-2 agonist is clonidine. It is helpful to deal with blushing and flushing. But it has side effects. One can feel drowsy or/and one’s blood pressure may also plummet. So, to neutralize this effect, one can use monoxidine as an alternative. Monoxidine has lesser side effects. But many do not find it as effective as clonidine. Propanolol is an ideal beta blocker. It is akin to α-2 agonists. And, it has been found to be effective in dealing with recurrent social blushing rather than the general rosacea flushing. 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Trying to find a hoodia 1000 mg product is not easy. Many companies advertise a 1000 mg product, but reading the fine print on the back or the diet pill bottle does not always support their claims. There are many diet pills containing hoodia gordonii on the market. Sometimes finding a diet pill containing genuine hoodia gordonii is the problem. Compared to a stimulant containing diet pill, hoodia gordonii appears to be much safer. Effectiveness seems to vary among individuals and there is no accepted standard dosage, however many people report that it takes about 3000mg per day to suppress their appetites. In order to avoid taking numerous pills throughout the day and to keep the cost per day at a more reasonable level, we searched for hoodia 1000 mg products. This is what we found. The first problem is finding a diet pill hoodia gordonii product that actually contains 1000 mg of hoodia gordonii. We looked at Hoodia Xtra 1000. The name seems to suggest -- at least to us -- that it is a hoodia 1000 mg product, but each capsule only contains 500 mg. They listed the recommended dosage as two capsules. An advertisement led us to ebay, where many companies sell hoodia products. One would think that that the diet pill hoodia gordonii 5000 contains 5000 mg per capsule, but each capsule actually contains 250 mg of a 20:1 extract. There is no exact equivalency from extract to powder. Some companies claim that twenty pounds of plant are used to create one pound of extract, but it is actually 20 grams or whole plant to create one gram. This does not mean that the extract is twenty times stronger, but that is what they would like for you to believe. The diet pill hoodia gordonii 1000 SRT claims to be a hoodia 1000 mg product, but is sold by a site that sells arts and crafts and has no certifications of authenticity. The price is nice, but really cheap products with no certificates of authenticity are risky in our opinion since you may not be getting genuine hoodia gordonii. The bionutricals diet pill hoodia 1000 is supposed to be 1000 mg, but the recommended dosage is two capsules, three times a day, which would be 6000 mg and no one recommends a dosage that high. They do not show an enlargement of the back of the bottle, so we can not verify the content. The only diet pill hoodia gordonii product that we could find that actually is a hoodia 1000 mg capsule that we could find is Hoodia XR. We have written a lot about Hoodia XR and we wanted to be able to compare it to other products containing the same amount of genuine hoodia gordonii. But, it turned out that we could not find any. If we do, we’ll let you know. For more information about hoodia 1000mg products, visit the Hoodia Info Blog.