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The Prostate: Part I – BNP What is situated below a body of water, has four zones and is commonly associated with venial pleasures. No it is not some romantic European city, but rather a walnut sized male organ that serves important procreative functions. It also happens to be an organ that plagues men as we age. This organ or gland is the prostate. This is the first of two articles on the male prostate. This article will focus on a disease process that affects older men, something we refer to as benign prostatic hyperplasia (BPH). BPH is a non-cancerous growth in the size of the prostate gland that impairs the flow of urine out of the bladder. The second article will focus of prostate cancer. But first a little about the small yet important male organ. The gland is located just below the bladder. It usually measures one inch by one-and-a-half inches (approximately the size of a walnut). It surrounds the urethra (the tube that takes urine out of the bladder). It is responsible for producing a fluid important in male sexual function. In the past the prostate was described as having “lobes”, but today we refer to it as having concentric zones. These zones are important both on an anatomical as well as histological level. We can separate pathology along these zones as well. For instance most all cancers occur in the peripheral zone while the benign process of enlargement occurs almost exclusively in the transitional zone (which only occupies about 5% of the total prostate volume). The prostate gland is also made up of different cell types. Cancer cells develop from the epithelial cells, but it is the interaction with stromal cells that is important in the behavior of the cancer. BPH develops from an interaction between these cells as well, but it is complex and poorly understood. Testosterone and other hormones and their interactions with this gland are hot topics of research in understanding prostate disease. The prostate gland produces most of what is found in the male ejaculate. The average volume is about 3 mL. This is less than a teaspoon and only 1% of it is sperm. The majority of the semen volume is made of products of the seminal vesicles and the prostate. The male ejaculate is very rich in potassium, zinc, citric acid and fructose. Along with these substances it also contains prostaglandins. There are many other unusual substances found in the semen. Not all is know about their function or purpose. This important male organ is a complex mix of anatomical structures and cell types that make it possible for human reproduction. However beyond the reproductive years of men, this organ becomes one of burden rather than usefulness. We will discuss the finer points of BPH and how to best avoid it and if plagued with it, treatment options. BPH typically affects men from their fourth to fifth decade of life and beyond. Several hormones come into play that have a drastic effect on the transitional zone (the zone that is most central and surrounding the urethra). Namely a metabolite of the male androgen Testosterone called Dihydrotestosterone (DHT) plays a big part on the enlargement of cells of the prostate and the encroachment on the urethra. There are several signs and symptoms that correlate with BPH and they are: slow urinary flow, the urge to urinate all the time, nighttime urination, enlargement and distension of the bladder with continuous urine leakage (incontinence) and urinary obstruction. Autopsies suggest that more than 90% of men older than 70 years have BPH. The average age for symptomatic development is about 65 years for white Americans and about 60 years for African-American men. Ways to prevent the effects of DHT on the prostate gland and the ensuing enlargement are via medications that block the enzyme 5-alpha-reductase, which converts Testosterone to DHT. Proscar is such a drug commercially available through a pharmaceutical company. Proscar works on blocking the effects of androgens on the epithelial cells and can actually shrink the size of the prostate making some of the symptoms of BPH resolve. Alternatively two FDA approved drugs that aid in symptoms of BPH (but act differently than Proscar) are Hytrin and Cardura. Both Hytrin and Cardura are drugs in the alpha1-blocker class. Originally researched as a centrally acting blood pressure reducer for patient with hypertension, it was discovered that this drug would actually relax the prostate tissue surrounding the urethra making symptoms of BPH resolve. Side effects generally include low blood pressure, dizziness, and nasal stuffiness. While neither of these two drugs will “cure” or reverse the process, they certainly do provide symptom relief for the patient plagued with BPH. Another way to treat this disease and a more natural approach is the use of herbs know for their anti-androgenic effects on the prostate. These include the well-studied Saw Palmetto herbal extract that blocks 5-alpha-reductase in the same manner as the prescription drug. Saw Palmetto taken in a standardized dose of 160mg twice daily has shown increased urine flow, with minimal side effects. Saw Palmetto is an herb indigenous to the Lowcountry of Georgia and South Carolina. Pygeum Africanum is shown to do the same yet it is not as effective and there is a fair degree of stomach symptoms. Pygeum is derived from an African evergreen tree. Stinging Nettles (Radix urticae) is another herb used widely in Europe for prostate health that has been shown to lower the residual urine volume in men with enlarged prostates. These phytotherapeutics (plant derived medicines), used and described by the Egyptians as far back as the 15 Century B.C., have a common compounds called phytosterols. The most effective phytosterol is beta sito sterol for BPH. None of the medications or herbs has been shown to prevent prostate cancer. These prescription medications and herbs are for the treatment, reduction in size or prevention of the benign process of enlargement of the prostate. Prostate cancer prevention and treatment is by other means and the subject of the next article. Besides the herbal and drug therapies there are a few surgical therapies worth mentioning. These include the most common transurethral resection of the prostate or TURP. This is where under the care of an urologist the constricted urethra within the prostate gland is “reamed out” thus mechanically or surgically widened the opening. A variant of this is the transurethral incision of the prostate (TUIP) where an incision rather than resection of the tissue is performed. A suitable procedure for patients with prostates 100 mL in volume. This involves an abdominal operation and removal of the whole prostate. Of course symptoms mentioned above for TURP are of greater frequency with this more radical procedure. There is also thermotherapy (a type of microwave treatment) that alleviates irritative symptoms, but not much is available in long-term results in the medical literature. And finally stent placement is an option. This can be used in selected cases of patients with a poor general condition and in the non-operative candidate. Symptoms of BPH include: Obstructive symptoms: Hesitancy in initiating voiding (trouble getting started) Weak urinary stream, prolonged voiding Post-voiding dribbling (mild incontinence) Sensation of incomplete emptying Nocturia (night time urination) Overflow incontinence Acute urinary retention (very painful condition) Irritative symptoms: Dysuria (discomfort in urination) Frequency Urgency Scoring BPH: The American Urological Association Symptom Index (AUASI) and International Prostate Symptom Score (IPSS) are now considered the gold standard measurement tools for the assessment of BPH symptoms and response to treatment. Both questionnaires can be used by a physician in a clinical practice to quantify the subjective symptoms of BPH and monitor therapies. Part II in this series will cover annual examination of the prostate, blood testing, prostate cancer. It will also cover prevention and treatment of prostate cancer. Reference: http://www.prostatehealth.com Lowe, FC. Et al, Phytotherapy in treatment of benign prostatic hyperplasia: a critical review. Urology 48:12-19, 1996 Dreikorn, K. et al, Stellenwert von Phytotherapeutica dei der Behandulng der benighnen Prostatahyperplasia. Urologe (A)34:119-129, 1995 Fitzpatrick, J.M. et al, Phytotherapeutic Agents in Management of Symptomatic Benign Prostatic Hyperplasia. Urological Clinics of North America. 22:407-412, 1995 Wilt T, Ishani A, Mac Donald R.. Serenoa repens for benign prostatic hyperplasia. The Cochrane Database of Systematic Reviews 2002, Issue 3. Art. No.: CD001423. DOI: 10.1002/14651858.CD001423. [Research by Sagalowski and Wilson, 1998] © 2005 home penis enhancement free exercise tip for penile enlargment real penis enlargement buy penis enhancement pills com enlargement pennis pennis pump penile enlargement video herbal penis enlargement pill pennis enlargement pic online vigrx
This article is designed to help those who've never changed a disposable diaper before, or think they're doing something wrong. Step 1. Gather all necessary items before starting. You'll need: clean diaper, baby wipes, baby powder, cream for rashes, and a disposable bag. Step 2. Wash your hands. Step 3. Cover changing area with cloth or waterproof blanket. Step 4. Place baby on changing table and secure him, or on designated area. Do not place on counter he can roll off of. Step 5. Fully remove child's pants or anything that may get in the way of diaper changing process. Step 6. Unfold clean diaper, sliding tabbed portion underneath the child. The front of the diaper, generally with little pictures on the top, should be face down. Step 7. Open tabs on dirty diaper and fold down. Do not remove yet. If child is a boy, cover penis with baby wipe or cloth to avoid spraying. Step 8. Hold baby's legs up with one hand. Wipe the baby's bottom clean. If it's a girl, make sure you always wipe front to back. If it's a boy, be sure to clean all around the scrotum. Put used wipes in the dirty diaper, use as many as you need until wipe comes away clean. Step 9. Pull soiled diaper out, fold and secure tabs. Put it in the disposable bag. Step 10. Apply powder to bottom. If there is a rash, let it air dry or pat dry with a cloth before applying cream. Do not put powder on rash. Step 11. Fold front of clean diaper up and secure tabs. Diaper should be snug without pinching. Make sure side ruffles are out, not in, to prevent leakage down the legs. If this is a newborn baby with umbilical cord, fold the diaper down to just below cord. Congratulations! You have changed a diaper. One last helpful tip. Have you experienced the "magic pee" with your baby boy, where the diaper is dry, but his clothes are wet? Here's the thing you need to watch for: Make sure the boy's penis is pointing down when putting on diaper. This is something I wish I knew when I first started changing diapers. If he is pointing up or to the side, his pee will shoot right out of the diaper. Remembering this will prevent many clothes and bedding changes. Good luck with the new addition to your family. free penis enlargement pill manual penis enlargment truth about pennis enlargement pills truth about penis enhancement penis enhancement pic do penis enlarement pills really work penis enlargement surgery photo enlargment free penis pills sample online vigrx
On April 14th of 1945, I was five years old. I came in from playing and was met by my mother who was sobbing. "Your other mother is dead," she said. I felt very sad, but for my adoptive mother. I never knew who my birth-mother was and never even considered the fact that I had another mother somewhere. I later found out that all the records associated with my adoption were supposed to have been sealed. So how could Mom have known that? I had a little bit of information about my birth. One such fact was that I suffered from hypopladia, "a condition I inherited from my father." It turns out that means that the opening of my penis was at the bottom rather than at the end. Of all the things to inherit! I also knew that I was born at General Hospital in Minneapolis, and that Mom and Dad were listed as the parents. That was all I knew for more than forty years. Mom died in 1985 and Dad in 1987. I was named executor of his estate. When I went through the papers I found a baptismal record for Richard Allen Hemmingsen, born on my birthday! Three names were listed as witnesses. After fighting with myself for a week I looked one name up in the phone book and called. A woman answered and I asked if Lloyd was there. The woman said he wasn't, but she would have him call me. I never heard from him and in the meantime, my ardor to find my birth family had subsided. Evie's father died a day after my mother on Christmas Day in 1985. When her mother died in 1987 she decided that she wanted to find out about her birth mother. She didn't have any feelings of betrayal. Nor did I. The laws that sealed the records in the early 1940s had been changed, and it was now possible to contact birth relatives, if both parties agreed to the contact. She wrote a long letter explaining all the things that had happened to her in her life and her views about politics and religion. To her delight, she got a response! Her mother was now living in Michigan and wanted to meet her. They did at the Minneapolis airport. An aunt was with her. In a long conversation, Evie learned that she had two half-sisters, a half-brother, and several aunts and uncles who were all very anxious to meet her. One aunt looked exactly like her. Her siblings were thrilled, and so was the man her birth-mother had married. He was a retired minister and had known about Evie for as long as they were married. We have had a warm relationship with the whole family for nearly twenty years. Unfortunately it has been shrinking because of deaths, but Evie still meets with a favorite aunt at least once a month. Her experiences finding her birth-family became a feature article in the Minneapolis Sunday paper. My path was a bit different. After Evie connected with her family, I again decided to try to find mine. Lloyd was still unavailable, but there were two other names on the baptismal certificate. I found one of the names in the Minnneapolis phone book. When I called him, he said, "You must be one of Hilma's twins." I told him that I was born in 1940. No, my uncle said. "The twins were born in 1944." You can imagine how excited I was to hear that! He said that she had died of internal bleeding one day after giving birth to twin boys. Ironically, my half-sibs were born on the same day as my adoptive sister, but a year later. I found out where Hilma was living when the twins were born and immediately placed a personals ad in the local newspaper asking whether anyone had information about the whereabouts of twin boys born in April of 1944. No one responded. In the meantime my new uncle arranged for me to meet with the rest of the family. It was huge; Hilma had had 10 siblings. An aunt threw a potluck lunch and the thirty some relatives all showed up. One was the other signer of the baptismal certificate. I asked her about my twin brothers. "They aren't brothers," she said. "They were a boy and a girl. Everyone called them Jack and Jill." From that point, everything came together. We were able to locate the adoption agency and they located the adoptive mother. She said that both children were alive and well. Later that night I got a call from my brother, and a few days later, my sister. Bro looks like me, but a bit heavier. We met my sister in Montana and visited Yellowstone Park together. We were both delighted. I have kept in contact with my Minnesota family. I have yet to visit my brother but I get regular letters from my sister. One of my aunts gave me a photo album of my mother. One, showing her on a bicycle with a friend, looked so much like me that we showed it to one of Evie's buddies. "That's John in a dress," Evie said, smiling. "Oh," said our friend. "Who's that with him?" My last words are advice for others who may be in our situation. Things don't always work out as well as they did for Evie and me, but if they do, it's like stepping into a different world, the alternative universe you always wondered about. com enlargment penile penile pump vimax enlargement free penis pills sample penis enargement surgeon vimax natural penis enlargement technique enlargment free penile pills sample herbal penis enlarement penis enlarement surgeon natural penis enlargement technique online vigrx
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